Clinical Studies

Clinical Studies supporting the gamete and mucosal safety of the Therio-gel patented, isotonic formula:

Effect of an Isotonic Lubricant on Sperm Collection and Sperm Quality. Fertility & Sterility. 2013 In Press

Is Wetter Better? An Evaluation of Over-the-Counter Personal Lubricants for Safety and Anti-HIV-1 Activity. PLoS One. 2012;7(11):e48328. 

Quantitative Perceptual Differences Among Over-the-Counter Vaginal Products Using a Standardized Methodology. Contraception. 2011;84:184-193

Sperm Toxicity of "Nonspermicidal" Lubricant and Ultrasound Gels Used in Reproductive Medicine. Fertility & Sterility. 2011 Feb;95:835-836

Impact of Glycerol-free Versus Glycerol-containing Fertility Lubricants on Sperm Function: Including Ability to Fertilize and Support Embryo Development in an In Vitro Model. Fertility & Sterility. 2010 Sept(Suppl);94:209-210

Effect of an Isotonic Fertility Lubricant on Sperm Penetration into Bovine Cervical Mucus in Vitro. Fertility & Sterility. 2010 Sept(Suppl);94:210 

Preservation of Beluga (Delphinapterus leucas) Spermatozoa Using a Trehalose-based Cryodiluent and Directional Freezing Technology. Reproduction, Fertility & Development. 2010;22:653-663

Effect of Lubricants Developed for Fertility Markets on In Vitro Fertilization and Embryo Development. Journal of Andrology. 2009 Mar/Apr(Suppl):53

Equine Breeding Management and Artificial Insemination. J Samper © 2009

Comparative Effect of “Non-spermicidal” Lubricants on Stallion Sperm Function. Animal Reproduction Science. 2008 Sept;107:360

Mucosal Irritation Potential of Personal Lubricants Relates to Product Osmolality as Detected by the Slug Mucosal Irritation Assay. Sexually Transmitted Disease. 2008 May;35:512-516

Effect of Vaginal Lubricants on Sperm Motility and Chromatin Integrity: A Prospective Comparative Study. Fertility & Sterility. 2008 Feb;89:375–379

Semen Collection, Characterisation and Artificial Insemination in the Beluga (Delphinapterus leucas) Using Liquid-Stored Spermatozoa. Reproduction, Fertility & Development. 2008;20:770-783

The Effect of Different Lubricants on Longevity of Motility and Velocity of Stallion Spermatozoa. Theriogenology. August 2007:496

Animal Model Study of a New Patient Lubricant’s Affect on In Vitro Fertilization & Embryo Development. Journal of Andrology 2007;Mar/Apr(Suppl):28

The Effects of Vaginal Lubricants and Moisturizers on Computer Assisted Sperm Analysis (CASA) Parameters Associated with Cervical Mucus Penetration. American Society of Reproductive Medicine Annual Meeting, Philadelphia PA, October 2004

Effects of Personal Lubricants on In Vitro Fertilization and Embryo Development. American Society of Andrology Annual Meeting, Phoenix AZ, March 2003

Polysaccharides Containing Arabinose and Galactose Decrease Oxidative Damage to Sperm In Vitro. American Society of Andrology, Montreal Quebec, June 2001

Veterinary lubricant for horse breeding and dog breeding
For Animal Use Only

User Story

“Our mare had huge open wounds on both her back legs due to a fence injury. It has taken a year of nursing to get her back to functioning. At first we tried every salve and ointment under her dressings. Then we switched to Therio-gel* and it was amazing! It really helped her heal faster and the tissues looked clean and healthy each day when we changed the bandages.”

JC, Spangle WA

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